Diosmina suppresses pro-inflammatory mediators in lipopolysaccharide-induced RAW264. 7 Macrophages through NF-κB and MAPK signaling pathways. Diosmina suppresses pro-inflammatory mediators in lipopolysaccharide-induced RAW264. 7 Macrophages. The purpose of this study is to study the molecular mechanism of diosmin in relation to the signaling pathways of NF-κB and MAPKs. By providing the information contained in this document, we do not diagnose, treat, cure, mitigate or prevent any type of disease or medical condition. Before undertaking any natural, integrative or conventional treatment, it is recommended to consult a licensed physician. More than 500 pages with alternatives and information about natural medicine. Godmine is an unsaturated flavonoid found in citrus fruits. This website is for informational purposes only. Otherwise, click here to become a member. Some features are currently only available to members.