Our data show that surgery has a proapoptotic effect on NCSCLC and for the first time offer a new non-enzymatic anti-apoptotic role for this old NCSCLC enzyme. Oleuropin-induced apoptosis is mediated by mitochondrial glyoxalase 2 in cells A5 of NCSCLC49: mechanical interior and possible new nonenzymatic role for the old enzyme. On the other hand, OP does not change the behavior of harmless human cells BEAS-2B or expression of mGlo2, which suggests that this bioactive compound plays a specific role in the NCPLC in cancer control. Recent results show that PO has a proapoptotic effect on NCSCLC cells through the apoptotic mitochondrial pathway. These data indicate a new way in which oleuropein has a proapoptotic effect on NCSCLC. This study investigated whether and how Glo2 is involved in the proapoptotic effects of operations on A5 NCSCLC cells49. In addition, our data show that the proapoptotic function of mGlo2 observed after surgery is due to the interaction of mGlo2 with the proapoptotic protein Bax. However, recent data indicate that Glo2 may also play a nonenzymatic role in some malignant cells. By providing the information contained in this document, we do not diagnose, treat, treat, mitigate or prevent any disease or health condition. It is recommended that you consult a licensed physician before performing any natural, integrative, or routine treatment. More than 500 pages of alternatives and information on natural medicine.