Relationship between the intestine and infection – Several studies show a correlation between the development of microscopic colitis after intestinal infection or improvement of symptoms with the administration of antibiotics to eliminate the infection and in some cases both. Other medical recommendations such as not taking NSAID, a low-fat, low-fiber diet, and imodium lead to the same problem: they do not address the root cause. CD is more common in women over 40 years of age, and it is estimated that 10-30% of patients examined for chronic diarrhoea are diagnosed with microscopic colitis in biopsy. This devastation can lead to several things, including allergies, skin problems, brain fog, autoimmune disease and – as you guessed – microscopic colitis. Histamine metabolic disorders occur primarily in the form of collagen from the disease, but also in IgA anti-gliadin antibodies in the intestines. The differences between the two types are minimal: in collagen colitis, there is a clear thickening of tissues in the large intestine. Of all autoimmune diseases, celiac disease appears to have the strongest association, as patients with CD are 50-70 times more likely to develop celiac disease than the general population. And that’s exactly what’s worrying us today, the leading cause of autoimmune diseases. It is almost impossible to ignore the fact that intestinal leakage is part of the cause and solution of microscopic colitis. CD is strongly associated with haplotype HLA-DR3-DQ2, which is also found in celiac patients. Biopsy can be performed during colonoscopy, a common procedure in which a flexible tube and a camera are used to photograph the inner surface of the large intestine. No specific autoantibodies have been confirmed so far, but there is strong evidence of an autoimmune base for both types of microscopic colitis.