Royal jelly reduces the cadmium-induced nephrotoxicity in male rats. The aim of this study was to study the protective effect of royal jelly on cadmium-induced nephrotoxicity. The concentration of Cd in the kidney tissue and the absolute kidney weight of the Cd-treated rats was significantly higher than in the control group. Histopathological studies showed that there is vacuum and obstruction of glomeruli in the renal tissue of CD-treated mice. However, all changes caused by this CD were mitigated by pretreatment with real jelly. Exposure to cadmium causes nephrotoxicity through the mediation of oxidative stress, inflammation and apoptosis. By providing the information in this document, we do not diagnose, treat, cure, alleviate or prevent any disease or medical condition. Before carrying out any natural, integrative or conventional treatment, it is recommended that you consult a licensed physician. Otherwise, click here to become a member.