Paeonia lactiflora Paeoniflorin – Paeoniflorin the main

Paeoniflorin, the main active ingredient in the roots of Paeonia lactiflora, suppresses bleomycin-induced pulmonary fibrosis in mice by suppressing the synthesis of type 1 collagen. Paleoniflorine reduces pulmonary fibrosis by suppressing type I collagen synthesis. However, it had little influence on the mRNA expressions of MMP-1 and TIMP-1 in the lung tissues of mice. The content of collagen type I, TGF-β1 and IFN-γ has been recognized by ELISA. By providing the information contained in this document, we do not diagnose, treat, cure, mitigate or prevent any type of disease or medical condition. Before undertaking any natural, integrative or conventional treatment, it is recommended to consult a licensed physician. The roots of Paeonia lactiflora Pall are generally used to alleviate the symptoms of this disease by promoting blood circulation and eliminating congestion.