Effect of lyophilized papaya leaf juice on the production of inflammatory cytokines during dengue virus infection in AG129 mice. Effect of freeze-dried Cari leaves juice on production of inflammatory cytokines during dengue virus infection. BACKGROUND: Papaya leaves have been used for traditional dengue treatment and are believed to have an immunomodulatory effect by influencing the level of cytokine production in vitro and in vivo. The gene expression study identified 8 inflammatory genes from regulated cytokines in the liver of AG129 infected mice treated with FCPLJ. CONCLUSION: The results demonstrated the potential immunomodulatory role of JFCPLF during a dengue virus infection in AG129 mice. METHODS: AG129 mice received oral FCPLJ for 3 days after 24 hours of dengue virus vaccination. Due to the lack of adequate in vivo results in the dengue model, this study was performed to study and identify cytokines affected by lyophilized C. The results of this study were used to evaluate the effects of dengue vaccination on the development of the disease. Before carrying out any natural, integrative or conventional treatment, it is recommended that you consult a licensed physician. By providing the information in this document, we do not diagnose, treat, cure, mitigate or prevent any disease or medical condition. More than 500 pages of alternatives and information on natural medicine.