In this study, the therapeutic effect of curcumin in acute myocardial infarction in rats was studied. Curcumin is presented as improved myocardial infarction by inhibiting cardiotoxicity. By providing the information contained in this document, we do not diagnose, treat, cure, mitigate or prevent any type of disease or medical condition. Before undertaking any natural, integrative or conventional treatment, it is recommended to consult a licensed physician. More than 500 pages with alternatives and information about natural medicine. The number of apoptotic cells was determined using the terminal deoxynucleotydyltransferase from theUTP nick end tagging assay. Curcumin is presented as a polyphenolic phytocomponent with corresponding cardioprotective properties. Many attempts have been made to improve pathological changes after myocardial infarction.