From the results of the phytochemical analysis of the extracts we can conclude that the composition of phenolic compounds does not differ significantly, and the main differences are related to amino acids, which unambiguously affect the overall pharmacological effect. The results obtained indicate the presence of anxiolytic activity in the feverfew extracts under study in complex with amino acids. The results indicate the presence of anxiolytic activity in the feverfew extracts under study. The most promising compounds were dry extracts modified by adding small amounts of arginine, valine, phenylalanine, glycine, lysine, and alanine. A total of 15 major phenols were found in the extracts, eight of which were identified. Extracts containing glycine, valine, and arginine were most effective in reducing anxiety in animals. In providing the information contained herein, we do not diagnose, treat, cure, alleviate, or prevent disease or illness of any type. It is recommended that you seek the advice of a qualified medical professional before beginning any natural, integrative, or conventional treatment. It should be noted that the extracts contain significant amounts of ellagic acid. Phytochemical and psychotropic studies in mammals L. Chlorogenic and caffeic acids were the dominant hydroxy acids.