Oral administration of NAS significantly suppressed the disease activity index and improved colonic histological lesions in a model of DSS-induced colitis. Synomenin attenuated sodium dextran sulfate-induced colitis. By providing the information contained herein, we are not diagnosing, treating, curing, alleviating, or preventing any disease or medical condition. Levels of tumor necrosis factor-α, interleukin-6, and inducible nitric oxide synthase were also decreased, as demonstrated by quantitative reverse transcription polymerase chain reaction. Before starting any natural, integrative, or traditional treatment, it is advisable to seek the advice of a licensed physician. In addition, INS reversed the decrease in colon length and superoxide dismutase activity in the colon. Over 500 pages of information and alternatives to natural medicine. This site is for informational purposes only. Some features are currently available to members only. Therefore, INS may have potential use as a protective drug for UC patients.